EDUCATIONAL QUALIFICATION

• Ph.D. : Department of Chemistry, Indian Institute of Science, Education and Research (IISER), Pune, 2020.
• PG : M. Pharm. (Specialization: Quality Assurance Techniques), MET’s Institute of Pharmacy, S P Pune University, Pune, 2013.
• UG : B. Pharm., NCRD’s Sterling Institute of Pharmacy, University of Mumbai, 2011.

Experience/ Research / Publications :

• Total Experience: 2 years as Postdoctoral Research Associate (Mentor: Prof. R. V. Hosur) at UM-DAE Center for Excellence in Basic Sciences, Mumbai.
• Area of Research: Biomolecular NMR Spectroscopy, Herbalomics.
• Total Papers Published: 11
• Membership: Nuclear Magnetic Resonance Society (NMRS) India.

ACADEMIC RECORDS

• Ph. D. : Organic Chemistry, IISER Bhopal (2017)
• M. Sc. : Chemistry, Acharya Nagarjuna University, Guntur, A.P. (2009)
• B. Sc. : (Chemistry, Mathematics and Physics), Sir C.R.R. College, Eluru, A.P. (2007)

EXPERIENCE :

• Assistant Professor, Indrashil University, October 2021 to Present
• Post-doctoral fellow, Dept. of Chemical Engineering, Yeungnam University, S. Korea (2019)
• Post-doctoral fellow, Institute of Chemistry, Hebrew University of Jerusalem, Israel (2018)
• Project research assistant, Dept. of Chemistry, IISER Bhopal (2017)

TEACHING EXPERIENCE :

• Teaching Assistant, Department of Chemistry, IISER Bhopla, 2013-14
• Lecturer at Sri Chalapathi UG and PG college, Eluru, A.P., 2010

RESEARCH PUBLICATIONS :

• web: https://scholar.google.com/citations?user=us4ahWIAAAAJ&hl=en

Papers Published in Peer Reviewed Journals

• Balkrishna S. J.; Prasad, C. D.; Panini, P.; Detty, M. R.; Chopra, D.; Kumar, S., Isoselenazolones as Catalysts for the Activation of Bromine: Bromolactonization of Alkenoic Acids and Oxidation of Alcohols, J .Org. Chem., 77, 9541, 2012. (I.F. : 4.81)
• Prasad, C. D.; Balkrishna, S. J.; Kumar, A.; Bhakuni, B. S.; Shrimali, K.; Biswas, S.; Kumar, S., Transition Metal Free Synthesis of Unsymmetrical Diaryl Chalcogenides from Arenes and Diaryl Dichalcogenides, J .Org. Chem., 78, 1434, 2013. (I.F. : 4.81)
• Prasad, C. D.; Kumar, S.; Sattar, M.; Adhikary, A.; Kumar, S., Metal Free Sulfenylation and Bis-Sulfenylation of Indoles: Persulfate Mediated Synthesis, Org. Biomol. Chem., 11, 8036, 2013. (I.F. : 3.88)
• Kumar, A.; Bhakuni, B. S.; Prasad, C. D.; Kumar, S.; Kumar, S., Potassium tert-Butoxide-Mediated Synthesis of Unsymmetrical Diaryl Ethers, Sulfides, and Selenides from Aryl Bromides, Tetrahedron, 69, 5383, 2013. (I.F. : 2.46)
• Kumar, A.; Yadav, A.; Verma, A.; Jana, S.; Sattar, M.; Kumar, S.; Prasad, C. D.; Kumar, S., Chemoselective Arylation of Phenols with Bromo-nitroarenes: Synthesis of Nitro-biaryl-ols and Their Conversion into Benzofurans and Carbazoles, Chem. Comm., 50, 9481, 2014. (I.F. : 6.22)
• Prasad, C. D.; Verma, A.; Sattar, M.; Kumar, S., Silver Mediated Thio-Acetoxylation and TFA Triggered Cyclization of Amino Disulfides with Unactivated Alkenes: Synthesis of 3-Aryl/Alkyl-1,4-benzothiazines, RSC Adv., 5, 75881, 2015. (I.F. : 3.12)
• Prasad, C. D.; Sattar, M.; Kumar, S., Transition-Metal-Free Selective Oxidative C(sp3)-S/Se Coupling of Oxindoles, Tetralone, Arylacetamides: Synthesis of Unsymmetrical Organochalcogenides, Org. Lett., 19, 774, 2017. (I.F. : 6.09)
• Verma, A.; Jana, S.; Prasad, C. D.; Yadav, A.; Kumar, S., Organoselenium and DMAP Co-Catalysis: Regioselective Synthesis of Medium-Sized Halolactones and Bromooxepanes from Unactivated Alkenes, Chem. Comm., 52, 4179, 2016. (I.F. : 6.22)
• Sattar, M.; Praveen; Prasad, C. D.; Verma, A.; Kumar, S.; Kumar, S., Palladium-Catalyzed C-H Functionalization of Ferrocene Carboxylic Acid by using 8-Aminoquinoline as a Removable Directing Group, Adv. Synth. Catal., 358, 240, 2016. (I.F. : 5.85)
• Sattar, M.; Rathore, V.; Prasad, C. D.; Kumar, S., TM Free Chemoselective Oxidative C-C Coupling of sp3 C-H Bond of Oxindoles with Arenes and Addition to Alkene, Chem. Asian J., 12, 734, 2017. (I.F. : 4.57)
• Kumar, S.; Rathore, V.; Verma, A.; Prasad, C. D.; Kumar, A.; Yadav, A.; Jana, S.; Sattar, M.; Meenakshi; Kumar, S., KOtBu-Mediated Aerobic Transition-Metal-Free Regioselective β-Arylation of Indoles: Synthesis of β-(2-/4-Nitroaryl)-indoles: Org. Lett., 17, 82, 2015. (I.F. : 6.09)
• Verma, A.; Patel, S.; Meenakshi; Kumar, A.; Sharma, S.; Jana, S.; Yadav, A.; Prasad, C. D.; Kumar, S.; Kumar, S., Transition Metal Free Intramolecular Selective Oxidative C(sp3)-N Coupling: Synthesis of N-Aryl-isoindolinones from 2-Alkylbenzamides, Chem. Comm., 51, 1371, 2015. (I.F. : 6.22) RSC
• Copper-Catalyzed Regioselective Oxidative Vinylsulfonylation of Quinoxalinones with Alkynes and Sulfonyl Hydrazides: Clinton, C. D.*; Prasad, C. D.*; Raju, T.; Lee, Y. R. Adv. Synth. Catal., 363, 776, 2021 (*Equal contribution) (I.F. : 5.85) Wiley
• Copper-Catalyzed Direct Oxidative Aroylations of Quinoxalinones with Methylarenes: Clinton, C. D.; Prasad, C. D.; Khanal, H. D.; Lee, Y. R. Asian J. Org. Chem. 10, 241, 2021. (I.F. : 3.32)

Papers in conferences :

• Prasad, C. D. and Kumar, S., “A Convenient Strategy for the Synthesis of Valuable Benzothiazine Derivatives” 2nd In-house chemistry symposium “Interactions” held at IISER Bhopal on September 5, 2015 (Oral Presentation).
• Prasad, C. D. and Kumar, S., “Persulfate Mediated Synthesis of Diaryl Chalcogenides and 3-Sulfenyl Indoles” 15th MTIC held at IIT Roorkee during December 13-16, 2013 (Oral Presentation).
• Prasad, C. D. and Kumar, S., “Transition Metal Free Synthesis of Unsymmetrical Diaryl Chalcogenides” 1st In-house chemistry symposium “Interactions” held at IISER Bhopal on August 30, 2014 (Oral Presentation).

REFERENCES :

• Prof. Sangit Kumar,
  Department of Chemistry,
  Indian Institute of Science Education and Research Bhopal,
  By-pass Road, Bhauri,
  Bhopal, M.P., India- 462 066
  Tel: +91 755 269 1317
  E-mail: sangitkumar@iiserb.ac.in
• Prof. Yong Rok Lee,
  School of Chemical Engineering,
  Yeungnam University
  280, Daehak-ro, Gyeongsan 38541,
  Republic of Korea
  Tel: 82–53–810–2529,
  E-mail: yrlee@yu.ac.kr
• Prof, Raed Abu-Reziq,
  Institute of Chemistry,
  The Hebrew University of Jerusalem,
  Jerusalem -91904, Israel
  Tel: +972-2-6586097
  Email: Raed.Abu-Reziq@mail.huji.ac.il
  

EDUCATIONAL QUALIFICATION

• Ph.D. (Biotechnology), 2015 Indian Institute of Chemical Biology-University of Calcutta
• M.Sc. (Biotechnology), 2007 University of Calcutta

Academic Credentials :

• Recipient of UGC-Dr. D.S. Kothari Postdoctoral Fellowship
• Postdoctoral research experience at Kyoto University, Japan and University of Florida, USA
• Awarded CSIR-JRF, SRF and eligibility for Lectureship
• Junior Research fellowship funded by the Department of Biotechnology
• GATE qualified; All India Rank – 5
• Summer research fellowship from the Indian Academy of Sciences
• 2nd rank in M.Sc. Biotechnology examination at the University of Calcutta
• 2nd rank in CSIR-Indian Institute of Chemical Biology Ph.D. Course Work
• Peer Reviewer for the Proceedings of the 10th International Conference on Biomedical Engineering and Biotechnology (ICBEB), China
• Keynote Speaker at the Virology virtual conference, Oxford instruments, 2021
• Good Clinical Practice (GCP) certificate from the National Institute on Drug Abuse, National Institutes of Health
• Collaborative Institutional Training Initiative (CITI) program on human subjects research, Johns Hopkins Bloomberg School of Public Health

Distinctions:

• Gold Medal in M Sc. First to qualify in CSIR-NET from Gujarat.

Original research articles published (PubMed indexed) – 6 :

• N-protein-RNA interaction is a drug target in a negative strand RNA virus. Chakraborty P, Chattopadhyay D, Roy S.
  Virus Res. 2021;295:198298. doi: 10.1016/j.virusres.2021.198298.
  PMID: 33508356.
• Density of CD3+ and CD8+ cells in gingivo-buccal oral squamous cell carcinoma is associated with lymph node metastases and survival.
  Mukherjee G, Bag S, Chakraborty P, Dey D, Roy S, Jain P, Roy P, Soong R, Majumder PP, Dutt S.
  PLoS One. 2020;15(11):e0242058. DOI: 10.1371/journal.pone.0242058.
  PMID: 33211709.
• Extract prepared from the leaves of Ocimum Basilicum inhibits the entry of Zika virus.
  Singh P, Chakraborty P, He DH, Mergia A.
  Acta Virol. 2019;63(3):316-321. DOI: 10.4149/av_2019_307.
  PMID: 31507198.
• Enhanced basepair dynamics predisposes protein assisted flips of key bases in DNA strand separation during transcription initiation.
  Roy NS, Debnath S, Chakraborty A, Chakraborty P, Bera I, Ghosh R, Ghoshal N, Chakrabarti S, Roy S.
  Phys Chem Chem Phys. 2018;20(14):9449-9459. DOI: 10.1039/C8CP01119B.
  PMID: 29565427.
• Construction and establishment of two minigenome rescue systems for Chandipura virus driven by recombinant vaccinia virus expressing T7 polymerase.
  Chakraborty P.
  Indian J Med Res. 2017;145(5):651-658. DOI: 10.4103/ijmr.IJMR_457_15.
  PMID: 28948956.
• A peptide targeted against phosphoprotein and leader RNA interaction inhibits growth of Chandipura virus – An emerging rhabdovirus.
  Roy A#, Chakraborty P#, Polley S#, Chattopadhyay D, Roy S.
  Antiviral Res. 2013;100(2):346-55. DOI: 10.1016/j.antiviral.2013.09.003. Epub 2013 Sep 13. # These authors made equal contributions.
  PMID: 24036128

Review articles published (PubMed indexed) – 1 :

• Immune and genomic signatures in oral (head and neck) cancer.
  Chakraborty P, Karmakar T, Arora N, Mukherjee G.
  Heliyon. 2018;4(10):e00880. DOI: 10.1016/j.heliyon.2018.e00880.
  PMID: 30417146

EDUCATIONAL QUALIFICATION

• Ph. D., Bhavnagar University
• M. Sc., Bhavnagar University

Professional Experience:

• Professor of Chemistry @ Indrashil University, Rajpur (2021- Present)
• Professor of Organic Chemistry @ M S University of Baroda (2008- 2021)
• Associate Professor/Reader @ M S University of Baroda (1995 - 2008).
• Brain Pool Visiting Scientist @ GIST Gwangju Korea (2001-2003).
• Lecturer @ M S University of Baroda (1993 – 1995).
• Research Associate @ Central University of Hyderabad (1988 – 1993).
• Senior Research Fellow CSIR @ IIT Mumbai (1986-1988).
• Junior Research Fellow CSIR @ Bhavnagar University. (1982 – 1986).

Distinctions:

• Gold Medal in M Sc. First to qualify in CSIR-NET from Gujarat.

Fields of Interest:

• Synthetic methodology, synthesis of bioactive molecules, natural products, strained molecules and macromolecules, Polymers, materials for future. Supramolecular Chemistry.

Publications:

• More than forty publications in reputed national and international journals. Delivered several invited talks and presentations in international and national meetings.

Research Guidance:

• 11 Ph Ds, 31 M Scs

Seminars and Conferences:

• Organized four National events. Participated in many national and international seminars and conferences.

Research Projects:

• Personal: Executed six major/minor/consultancy projects.
• Department: FIST/UGC-CAS.

Administrative Involvement:

• Member of Senate, The M S University of Baroda, 2001=2003
• Member, Faculty Board, Faculty of Science, The M S University of Baroda, 1997-2014; 2017-
• Member, Board of Studies in Chemistry, The M S University of Baroda ,1995-2014; 2017-
• Chairman of Board of Studies in Chemistry, The M S University of Baroda, 2017-2020
• Coordinator, Department of Environment Studies, Faculty of Science. The M S Univ. 2014-2016
• Associate Director, Department of Env. Studies, Faculty of Science, The M S Univ. 2016-2017
• Head, Department of Chemistry, Faculty of Science, The M S University of Baroda, 2021
• Member, Board of Studies in Chemistry, The M. K. University Bhavnagar, 2019-present.
• Member, Board of Studies in Chemistry. MIT-ADT University Pune, 2021-present
• Department: FIST/UGC-CAS.

Professional Affiliations:

• Indian Chemical Society
• Indian Science Congress
• Chemical Research Society of India
• Indian Association for Air Pollution Control
• SOCLEAN-Baroda

EDUCATIONAL QUALIFICATIONS

• Ph. D. : (Chemistry), 2014, Indian Institute of Technology, Kharagpur, WestBengal, India
• M. Sc. : (Chemistry), 2008, National Institute of Technology, Warangal, Telangana, India
• B. Sc. : (Mathematics, Physics and Chemistry), 2005, Hindu College, ANU University, Andhra Pradesh, India

WORK EXPERIENCE

• Adjacent Faculty (01/2021 – on going), Department of Chemistry, Indrashil University, Rajpur, Mehsana, India
• DST Inspire Faculty (02/2017 – on going), Applied Biology, Indian Institute of Chemical Technology, Hyderabad, Telangana, India
• Postdoctoral Fellow (05/2014 – 02/2017), Dalhousie Medicine New Brunswick, Canada
• Assistant Professor (08/2013-11/2013) Vellore Institute of Technology, Vellore, Tamil Nadu, India

Subject Taught

• Engineering Chemistry
• B.Sc. Chemistry (Physical Chemistry)
• M.Sc Chemistry (Analytical Chemistry)

PROFESSIONAL RECOGNITION, AWARDS, FELLOWSHIPS RECEIVED:

• I have completed project work in G.V.K Bio Labs (Innogent), Hyderabad
• I had all India GATE 2008 (326-rank), (94.81-percentile)
• I got all India 46th rank in NIT Warangal M.Sc. entrance examination in 2006
• I received NBHRF CIHR-SPOR-MSSU Govt. Post-doctoral Fellowship, New Brunswick, Canada
• Reynolds Fellowship for Post-doctoral Research at Dalhousie University, Canada
• I am selected as a DST Inspire Faculty, DST, Govt. of India-2016
• Received Best Oral Presentation by ACS Omega March 8-10, 2019, Berhampur University.

PROJECTS

• Chemically engineered nanoparticles for enhanced delivery and efficacy of chemotherapeutics in resistant strains of breast cancer-DST INSPIRE Scheme-35 Lakhs
• Chemically Engineered PDA Nanoparticles in Eliciting Innate Immune Response as Therapeutics in Glioma-201901HLC01RP05326-BRNS -New Young Scientist Research Award -25 Lakhs (Under Review)

List of graduate students mentoring

• Gayathri Koula UGC-JRF - Aug 2017 Registration (Co-PI, IICT)
• Kalpana Javaji ICMR-SRF July 2018 (Co-PI, IICT)
• Keerthi Bhamidipati - ICMR-SRF June 2019 (Co-PI, IICT)

List of Disseration students

• Chandan Kumar M (2017-2018)-M.Tech from Andhra University
• Vineet Ponnala (2018-2019)-M.Sc. from SRM University.

PRESENTATIONS/POSTERS IN CONFERENCE AND SYMPOSIUM

• Puvvada, N. Venkatesan, P.; Panigrahi, P. K.; Mandal, D.; Prashanth Kumar, B. N.; Mandal, M. Pathak, A., Preparation and Characterization of Different Hydroxyapatite Nanoparticles on Cancer Cells ( First World Conference on Nanomedicine and Drug Delivery. April - (2010), Invited Talk)
• Venkatesan, P.; Puvvada. N.; Pathak, A.; Mandal, M., Synthesis and Characterization of Celecoxib Loaded Hydroxyapatite Nanoparticle for Colon Cancer Treatment (First World Conference on Nanomedicine and Drug Delivery. April - (2010), Invited Talk)
• Naga Prasad Puvvada, Pravas Kumar Panigrahi, Sunil Kumar and Amita Pathak, Preparation and Characterization of Hydroxyapatite (HAP) Nanoparticles, poster presentation at International Workshop on Nanotechnology and Advanced Functional Materials, NCL Pune (2009).
• Pravas Kumar Panigrahi, Nagaprasad Puvvada and Amita Pathak, Synthesis of MoS2 Nanofibers by Aqueous Solution Method, poster presentation at 6th One-day National Symposium in Chemistry, Department of Chemistry, IIT Kharagpur (2008).
• Nagaprasad Puvvada, Venkatesan, P. Himani Kalita, Fisher, P. B.; Mandal, M. and Pathak, A. The potential of celecoxib-loaded hydroxyapatite-chitosan nanocomposite for the treatment of colon cancer. Presented poster at Diamond Jubilee Symposium on Recent Trends in Chemistry, Department of Chemistry, IIT Kharagpur (2011).
• Nagaprasad Puvvada was attended in The 2nd Global Cancer Genomics- Tata Memorial Centre Symposium from 19th – 20th Nov 2012.
• Nagaprasad Puvvada, Amna Rasul, Ashley Eadie, Sarah Melville, Jeremy A Simpson and Keith R Brunt Design and Synthesis of Nano-Hemin for the Treatment of Acute Myocardial Infarction, NBHRF Conference, CANADA, 2nd to 3rd November 2015.
• Naga Prasad Puvvada, Alli Murugesan, Stacy Grieve, Bithika Ray, Anthony Reiman and Keith R. Brunt. Translation of clinical-biophysics into clinical practice – use of blood-plasma SERS-Raman scattering during therapy to detect and track blood-cancer disease progression and predict patient outcome, MSSU-SPOR workshop, Canada, 22nd to 23rd March 2016.
• Nagaprasad Puvvada Design and Synthesis of Nano-Hemin for the Treatment of Acute Myocardial Infarction, presented oral talk International Conference on advanced Chemical Biology-2019 held at CSIR-IICT Hyderabad from 28th Feb2019 to 2nd March 2019.

Research Area

My primary research interests is to develop novel chemical synthesis processes tailored to biological conditions to develop compatible nanomaterials for drug delivery applications in medicine, that include: 1) Developing novel solution-based chemical processes for the preparation of a variety of biocompatible nano-sized materials in particulate form. 2) To standardize chemical synthesis methods for drug delivery applications in oncology (graduate training, IIT), cardiology (postdoctoral fellowship, Canada) and infectious disease (under development). 3) To combine chemistry, nanotechnology and their applications in medicine using cell biology and whole animal studies to advance clinical care. 4) To acquire and license intellectual property for the novel nanomaterial combinations developed for medicine.

The main research activities involved during my doctorate and post-doctorate studies involved the design and synthesis of novel biocompatible materials such as hydroxyapatite, magnetite, ZnO, Carbon nanoparticles and so forth. I have successfully synthesized HA-nanoparticles having high surface area by co-precipitation methods using complexing agents. The synthesized samples are characterized by various sophisticated analytical techniques, such as XRD, TEM, PSD and SEM analysis. Further analyses suggest that the synthesized hydroxyapatite powders under various complexing agents show effective restriction of nuclei growth (control the growth along the [001] and [100] axis) of the synthesized hydroxyapatite samples by ligands during precipitation process. The synthesized HA-nanoparticles are hemocompatibile in bulk aqueous media, which depends on the shape of the particles (i.e., needle-like shape). The present study has provided not only novel building blocks for the construction of artificial bones with novel mechanical properties but also a new strategy for the controlled growth of inorganic nanoparticles. This work can further be extended for investigating the effect of high surface area of the HA-nanoparticles for antitumor activity, apoptosis and apoptotic signalling activation protein levels (Nanoscale 2010, 2, 2631).

Further, the potential role of HA-nanoparticles used for drug delivery with chitosan as a tethering agent to delivery celecoxib for the treatment of Colon cancer is of interest. The drug loaded nanocarriers are well studied by characterization techniques particle size, zeta potential, crystallinity, functional group analysis, entrapment efficiency, drug release and hemo-compatibility and further validated nanocarriers performance in cell culture (in vitro) and animal (in vivo) models. The effects of celecoxib-loaded nanoparticles on colon cancer cell proliferation, morphology, cytoskeleton, cellular uptake and apoptosis were analysed in vitro. Further, we evaluated the anti-proliferative, apoptotic and tumor inhibitory efficacy of celecoxib-loaded nanocarriers in a nude mouse human xenograft model. Additional in vivo studies demonstrated significantly greater inhibition of tumor growth following treatment with this modified nanoparticle system. The present study indicates a promising, effective and safe means of using celecoxib, and potentially other therapeutic agents for colon cancer therapy (Biomaterials, 32 (2011) 3794-3806).

Similarly, I evaluated the fluorescence switching nature of Hollow ZnO-nanocarrier used for safe delivery of paclitaxel for the treatment of breast cancer. Further, a dual cell-specific (targeted drug delivery) and pH sensitive nanocarriers greatly improved the efficacy of paclitaxel to regress subcutaneous tumours in vivo (Nature Scientific Reports, 5 11760, 2015). In addition to that, shape dependent nanostructures have been prepared via a chemical method and subsequently their shape-dependent catalytical activity has been verified using various substrates (Pyrogallol, 4-nitrophenol etc.,). Their catalytical activity was validated for superior performance as shaped-nanoparticles [RSC Advances, 2012, 2, 3270–3273 and Journal of Catalysis, 336. 11-22 (2016)].

During my post doctorate studies (translational pharmacology and medicine), toxic effects of chemotherapy and the inability to deliver adequate doses of drugs to the affected site in the body have led to the fabrication and design of alternate delivery formulations that can provide site-specific targeting of therapeutics for myocardial (heart attack) therapy. The research work puts forward new methodologies for water-based synthesis of biocompatible, multifunctional Niosome based therapeutic delivery and gold micelles nanostructures, which have been designed as distinctive carriers and their efficacy towards site-specific delivery of several drugs have been evaluated for myocardial therapy.

The motivation was to synthesize stable, biocompatible nanostructures and suitably decorate them with flourophores, targeting agents (e.g., pH sensitive) and novel drugs for simultaneous assessment of targeted delivery of drugs to the problem site and diagnostic imaging (i.e. , MRI or Raman) allowing real time monitoring of cytoprotection.

Raman spectroscopy is a vibrational anti-stroke technique that can be used as an optical probe to assess molecular changes in disease states. The objective of our study was to explore the prognostic and predictive power of surface enhanced Raman spectra (SERS) using novel nanogold micelles in blood-cancers such as, leukemia, lymphoma, and myeloma. Plasma serum was collected from a bio-bank of samples derived iteratively from blood-cancer patients undergoing standard therapy in hospital. The corresponding SERS-spectra, as measured by Raman, were interpreted according to the patients’ ongoing health status. Healthy normal commercial plasma was used as a reference standard. SERS-spectra were measured from 200 to 1800 cm-1 at 514 nm excitation in 15-second signal. The SERS-spectra signal differed significantly between normal and blood-cancer patients in regions 950–1170, 1200–1350, and 1550–1675 cm-1 reflecting changes in tryptophan, phenyl alanine, nucleic acids, and phospholipids. These changes in percent-relative-signal discriminated normal from blood-cancer plasma and differentiated the clinical status amongst cancer patients. This demonstrates a technique with both diagnostic and prognostic value in medicine. The primary research reveals the potential to determine the blood-cancer diagnostic stage, therapeutic efficacy/response and progressive prognosis noninvasively. Further, we have developed an easy-to-use, clinical-scale to formalize this new field of clinical biophysics for rapid determination and decision guidance for clinicians (patents pending). These results could significantly improve patient-tailored therapy and clinical outcomes. Applying clinical-biophysics to standard practice, on par with clinical-chemistry, requires further integration and knowledge translation into patient care studies, such as these. My research goal is to establish Raman based diagnostics for several diseases in addition to Cancer through use nanoparticle amplification to better detect early onset and progression of disease and apply new innovative therapies.

Specific biocompatible materials of interest for drug delivery applications

• Synthesis of various biocompatible niosomal (or) inorganic nanomaterials and their usage in drug delivery applications in cancer, cardiovascular and infectious disease research.
• Synthesis of biocompatible nanomaterials for the delivery of genes like si-RNA for medical applications.
• The current work can be extendable to in vivo applications and bio imaging applications.

LIST OF SIGNIFICANT PUBLICATIONS (with details)
PUBLICATIONS IN JOURNALS

• Puvvada, N.; Panigrahi, P. K.; Pathak, A., Room temperature synthesis of highly hemocompatible hydroxyapatite, study of their physical properties and spectroscopic correlation of particle size. Nanoscale 2010, 2 (12), 2631-2638.
• Venkatesan, P.; Puvvada, N.; Dash, R.; Kumar, B. N. P.; Sarkar, D.; Azab, B.; Pathak, A.; Kundu, S. C.; Fisher, P. B.; Mandal, M., The potential of celecoxib-loaded hydroxyapatite-chitosan nanocomposite for the treatment of colon cancer. Biomaterials 2011, 32 (15), 3794-3806.
• Puvvada, N.; Kumar, B. N. P.; Konar, S.; Kalita, H.; Mandal, M.; Pathak, A., Synthesis of biocompatible multicolor luminescent carbon dots for bioimaging applications. Sci Technol Adv Mat 2012, 13 (4).
• Puvvada, N.; Mandal, D.; Panigrahi, P. K.; Pathak, A., Aqueous route for the synthesis of magnetite nanoparticles under atmospheric air: functionalization of surface with fluorescence marker. Toxicol Res-Uk 2012, 1 (3), 196-200.
• Puvvada, N.; Panigrahi, P. K.; Mandal, D.; Pathak, A., Shape dependent peroxidase mimetic activity towards oxidation of pyrogallol by H2O2. RSC Adv 2012, 2 (8), 3270-3273.
• Puvvada, N.; Panigrahi, P. K.; Kalita, H.; Chakraborty, K. R.; Pathak, A., Effect of temperature on morphology of triethanolamine-assisted synthesized hydroxyapatite nanoparticles. Appl Nanosci 2013, 3 (3), 203-209.
• Puvvada, N.; Rajput, S.; Kumar, B. N. P.; Mandal, M.; Pathak, A., Exploring the fluorescence switching phenomenon of curcumin encapsulated niosomes: in vitro real time monitoring of curcumin release to cancer cells. RSC Adv 2013, 3 (8), 2553-2557
• Karthik, S.; Puvvada, N.; Kumar, B. N.; Rajput, S.; Pathak, A.; Mandal, M.; Singh, N. D., Photoresponsive coumarin-tethered multifunctional magnetic nanoparticles for release of anticancer drug. ACS Appl Mater Interfaces 2013, 5 (11), 5232-8.
• Kumar, B. N. P.; Puvvada, N.; Rajput, S.; Sarkar, S.; Das, S. K.; Emdad, L.; Sarkar, D.; Venkatesan, P.; Pal, I.; Dey, G.; Konar, S.; Brunt, K. R.; Rao, R. R.; Mazumdar, A.; Kundu, S. C.; Pathak, A.; Fisher, P. B.; Mandal, M., Sequential release of drugs from hollow manganese ferrite nanocarriers for breast cancer therapy. J Mater Chem B 2015, 3 (1), 90-101.
• Rajput, S.; Puvvada, N.; Kumar, B. N.; Sarkar, S.; Konar, S.; Bharti, R.; Dey, G.; Mazumdar, A.; Pathak, A.; Fisher, P. B.; Mandal, M., Overcoming Akt Induced Therapeutic Resistance in Breast Cancer through siRNA and Thymoquinone Encapsulated Multilamellar Gold Niosomes. Mol Pharm 2015, 12 (12), 4214-25.
• Puvvada, N.; Rajput, S.; Kumar, B. N.; Sarkar, S.; Konar, S.; Brunt, K. R.; Rao, R. R.; Mazumdar, A.; Das, S. K.; Basu, R.; Fisher, P. B.; Mandal, M.; Pathak, A., Novel ZnO hollow-nanocarriers containing paclitaxel targeting folate-receptors in a malignant pH-microenvironment for effective monitoring and promoting breast tumor regression. Sci Rep 2015, 5, 11760.
• Konar, S.; Kalita, H.; Puvvada, N.; Tantubay, S.; Mahto, M. K.; Biswas, S.; Pathak, A., Shape-dependent catalytic activity of CuO nanostructures. J Catal 2016, 336, 11-22.
• Sarkar, S.; Konar, S.; Prasad, P. N.; Rajput, S.; Kumar, B. N. P.; Rao, R. R.; Pathak, A.; Fisher, P. B.; Mandal, M., Micellear Gold Nanoparticles as Delivery Vehicles for Dual Tyrosine Kinase Inhibitor ZD6474 for Metastatic Breast Cancer Treatment. Langmuir 2017, 33 (31), 7649-7659.
• Rao, B. R.; Kotcherlakota, R.; Nethi, S. K.; Puvvada, N.; Bojja, S.; chaudhuri, A.; Patra, C. R., Ag2[Fe(CN)5NO] nanoparticles exhibit anti-bacterial activity and wound healing properties. ACS Biomaterials Science & Engineering 2018, 4 (9), 3434-3449.
• Kumar, B. N. P.; Puvvada, N.; Rajput, S.; Sarkar, S.; Mahto, M. K.; Yallapu, M. M.; Pathak, A.; Emdad, L.; Das, S. K.; Reis, R. L.; Kundu, S. C.; Fisher, P. B.; Mandal, M., Targeting of EGFR, VEGFR2, and Akt by Engineered Dual Drug Encapsulated Mesoporous Silica-Gold Nanoclusters Sensitizes Tamoxifen-Resistant Breast Cancer. Mol Pharm 2018, 15 (7), 2698-2713
• Kanugala, S.; Jinka, S.; Nagaprasad P.; Banerjee, R.; C. Ganesh Kumara., Phenazine-1-carboxamide functionalized mesoporous silica nanoparticles as antimicrobial coatings on silicone urethral catheters Sci Rep 2019. 9, 6198.
• Harsha G. K.; Madhu Chakali; Ramanjaneya R Gontu.; Narendra Reddy Chereddy; Nagaprasad Puvvada; T.R. Baggi. A naked eye & ratiometric detection of Zn2+ and H2PO4- ions by imidazole-quinoline based fluorophore and its application in live-cell imaging Chemistry Select 2020, 5, 6059-6065.
• Mukherjee, Poulami; Kumar, Amit; Bhamidipati, Keerti ; Puvvada, Nagaprasad; Sahu, Sumanta Kumar. Facile strategy to synthesize magnetic upconversion NMOFs composite for theranostics application ACS Applied Bio Materials, 2020, 3, 869-880.
• Sopan, M; Wagalgave, Sachin, D. Padghan; Mohammad, Al. Kobaisi; Duong, Duc. La; Keerti, Bhamidipati; Nagaprasad, Puvvada; Rajesh, S. Bhosale; Sidhanath, V Bhosale; Sheshanath. V. Bhosale. Selectivity and bio-compatibility of self-assembled chiral flower-like and helical nanostructures New Journal of Chemistry, 2020 , 44 (41), 18092-18101.
• Sopan M. Wagalgave, Mahmood D. Aljabri, Keerti Bhamidipati, Deepak Shejule, Dinesh N. Nadimetla, Mohammad Al Kobaisi, Nagaprasad Puvvada, Sidhanath V. Bhosale, Sheshanath V. Bhosale. Characteristics of pH-directed aggregation-induced enhanced emission (AIEE) and nanostructure orchestrate via self-assembly of naphthalenediimide-tartaric acid bolaamphiphile: Role in cellular uptake. New J. Chem., 2021,45, 8775-8785.
• Saikat Dewanjee, Jayalakshmi Vallamkondu, Rajkumar Singh Kalra, Nagaprasad Puvvada, Ramesh Kandimalla and P. Hemachandra Reddy Emerging COVID-19 Neurological Manifestations: Present Outlook and Potential Neurological Challenges in COVID-19 Pandemic. Molecular Neurobiology., 2021 (https://doi.org/10.1007/s12035-021-02450-6)
• Stacy Grieve, Nagaprasad Puvvada, Angkoon Phinyomark, Kevin Russell, AnsarHassan, Jean-Francois Legare, Petra C. Kienesberger, Thomas Pulinilkunnil, Tony Reiman, Erik Scheme, Keith R. Brunt.Nanoparticle surface-enhanced Raman spectroscopy as 3 a non-invasive, label-free tool to monitor hematological 4 malignancy Nanomedicine (London), 2021 (Accepted)

Manuscripts under review

• Amit, K, M.S.; Archana, K.; Tinku S.; Shwetank, A.; Puvvada, N.; Gayathri, K.; Sumanta, K. S.; Carbon Dots Synthesized from Porcine Pancreatic Lipase; A Unique Turn-off Fluorescent Strategy for Selective Detection of Dopamine and Live Cellular Imaging Actuator B-Chem. 2021. SNB-D-21-03737.

Book Chapters

• Chityal Ganesh Kumar, Kanugala Sirisha and Puvvada Nagaprasad. Synthesis, Characterization and Applications of Silica Nanomaterials from a Nanobiotechnological Perspective, K418380, CRC Press ((ISBN 9780367200503))-2019.
• SERS nanomaterials for nano-device processing in cancer diagnostics Hari babu Bollikolla Basavaiah Chandu and Nagaprasad Puvvada (CRC Press, Invited Book submitted

Academic Records

• Post-Doc : Department of Chemistry, College of Natural Sciences, Hanyang University, Seoul, Republic of Korea. Supervisor: Dr. Hyosung Choi Research field: Synthesis of organic-inorganic hybrid materials and their application to hybrid optoelectronic devices (2019)
• Ph. D. : Indian Institute of Science Education and Research (IISER) Bhopal, Ph.D Course Work Physical Chemistry (CGPA 7.67) Supervisor: Dr. Abhijit Patra Dissertation: Conjugated Porous Organic Polymers: FluorescentBased Sensing, Photocatalysis and Energy storage (2018)
• M. Sc. : Vidyasagar University, Midnapore West Bengal, India Organic Chemistry Awarded First Class, 82.4%, Dissertation: Green Synthesis of Gold Nanoparticles and its Application as a Catalyst for the Reduction of 4-nitrophenol to 4-aminophenol (2012)
• B. Sc. : Ramananda Centenary College, University of Burdwan, West Bengal, India Awarded First Class, 64.0% (2010)

Fellowship

• NET, Council of Scientific and Industrial Research (CSIR)
• NET, Council of Scientific and Industrial Research (CSIR)

Professional experience

• Professional experience
• Investigated the mechanism of nitroaromatic quenching in porous organic polymer
• Polymer solar cell

Skills

• Strong background in synthetic organic / inorganic chemistry
• Conversant with handling air and moisture sensitive compounds using glove box and Schlenktechniques
• Proficient in spectroscopic techniques including IR, NMR, UV-VIS, EPR, Fluorolog, TCSPC
• Trained in Quantachrome BET instrument
• Trained in Gel permeation chromatography
• Familiar with conducting electrochemical experiments such as cyclic voltammetry
• Well versed with scanning electron microscopy and atomic force microscopy
• Knowledge in relevant software applications such as Mnova, Origin, Mercury, Scifinder,Chemdraw, CH-Instrument, and Material studio

List of Publications

Web: https://scholar.google.com/citations?user=nkkpHRoAAAAJ&hl=en

• Bandyopadhyay, S. :Pallavi, P.; Anil, A. G.; Patra, A. Fabrication of porous organicpolymers in the form of powder, soluble in organic solvents and nanoparticles: aunique platform for gas adsorption and efficient chemosensing. Polym. Chem. 2015, 6, (20), 3775−3780. (Featured as inside front cover page) (I.F. 5.687)
• Deshmukh, A.; Bandyopadhyay, S.; James, A.; Patra, A., Trace level detection ofnitroanilines using a solution processable fluorescent porous organic polymer. J.Mater. Chem. C 2016, 4, (20), 4427-4433. (I.F. 5.256)
• Bandyopadhyay, S.; #Anil, A. G.; # James, A.; Patra, A., Multifunctional porousorganic polymers: tuning of porosity, CO2, and H2 storage and visiblelight-drivenphotocatalysis. ACS Appl. Mater. Interfaces. 2016, 8, (41), 27669-27678. # Equal contribution (I.F. 7.504)
• Bandyopadhyay, S.; Metivier, R.; Pallavi, P.; Preis, E.; Nakatani, K.; Landfester, K.;Patra, A.; Scherf, U., Conjugated polymer nanoparticle-triplet emitter hybrids inaqueous dispersion: fabrication and fluorescence quenching behavior. MacromolRapid Commun 2016, 37, (3), 271-277. (I.F. 4.265)
• Pallavi, P.;# Bandyopadhyay, S.;# Louis, J.; Deshmukh, A.; Patra, A. A soluble conjugated porous organic polymer: efficient white light emission in solution, nanoparticles, gel and transparent thin film. Chem. Commun. 2017, 53, (7), 1257-1260. # Equal contribution(I.F. 6.290)
• Hussain, M. W.; Bandyopadhyay, S.; Patra, A. Microporous organic polymers involving thiadiazolopyridine for high and selective uptake of greenhouse gases at low pressure. Chem. Commun. 2017, 53, (76), 10576−10579. (I.F. 6.290)
• Bandyopadhyay, S.; Singh, C.; Jash, P.; Hussain, M. W.; Paul, A.; and Patra, A.; Redoxactive pyrene-based pristine porous organic polymers for efficient energy storage with exceptional cyclic stability Chem. Commun. 2018, 54, (50), 6796-6799. (I.F. 6.164)
• Bandyopadhyay, S#.;# Kundu, S#.;#Giri, A.; Patra, A design strategy for red emitting solution processable porous polymer: generation of reactive oxygen species with visible light Chem. Commun. 2018 , 54, (66), 9123-9126. (Featured as inside front cover page) (I.F. 6.164)
• Ko, S-J.; Heo, J.; Lee, B- H.; Ha, Su R.; Bandyopadhyay, S.; Cho, H J.; Choi, H.; Kim, J Y. Morphological and optical engineering for high-performance polymer solar cells ACS Appl. Mater. Interfaces. 2019, 11, 4705-4711. (I.F. 8.45)
• Bandyopadhyay, S.; Boukhvalov, DW.; Nayak, AK.; Ha, SR.; Shin, HJ.; Kwon, J.; Song, T.; Choi, H.; Redox active nitrogen-containing conjugated porous polymer: An organic heterogeneous electrocatalysts for oxygen reduction reaction Dyes and Pigments. 2019, 107557. (I.F. 4.018)
• Ryong Ha, S.; Hyeon Jeong, W.; Liu, Y.; Teak Oh, J.; Yong Bae, S.; Lee, S.; Won Kim, J.; Bandyopadhyay, S.; In Jeong, H.; Young Kim, J. et al. Molecular Aggregation Method for Perovskite–Fullerene Bulk Heterostructure Solar Cells. J. Mater. Chem. A 2020, 8, 1326-1334, (I.F. 10.77)

References

Dr. Abhijit Patra,

Department of Chemistry

Division of Physical Chemistry

Academic Building II, 3rd Floor

Indian Institute of Science Education and Research (IISER) Bhopal

Indore By Pass Road,Bhauri, Bhopal-462066, India

Tel: +917556691338

Email: abhijitpatra@iiserb.ac.in

Dr. Hyosung Choi

Department of Chemistry,

College of Natural Sciences,

Hanyang University, Seoul, Republic of Korea.

Tel: + 02-2220-2619

Email: hschoi202@hanyang.ac.kr

Dr. Ajay Kumar Misra

Department of Chemistry and Chemical Technology

Vidyasagar University,

Midnapore. West Bengal

Tel: + 913222298382

Email: ajay@mail.vidyasagar.ac.in

EDUCATIONAL QUALIFICATION

• M. Sc., Ph. D. (Microbiology)

PUBLICATIONS / ARTICLES / CONFERENCE

• Articles/Chapters Published in the books : 9 Books
• Published Papers in Journals (National or International) : 75 Papers
• Papers presented in Conferences, Seminars, Workshops, Symposia : 10 Papers

EDUCATIONAL QUALIFICATION

• UG : Chemistry, Botany, VBS Purvanchal University, Jaunpur, UP 2000.
• PG : Biotechnology, VBS Purvanchal University, Jaunpur, UP 2002.
• Ph.D : Biotechnology, Dr APJ Abdul Kalam Technical University, Lucknow, UP, 2009.

EXEPERIENCE / RESEARCH / PUBLICATIONS

• Total Experience in Years : 8 years
• Area of Research : Synthetic Biology, Metabolic Engineering, Genome Engineering
• Total Papers Published : 73 papers
• Total Books Published : 5 Books (Elsevier, Springer Nature)
• Other Achievements : 23 Book Chapters

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ACADEMIC QUALIFICATION

• B.Sc. In Biochemistry-Chemistry-Microbiology T.S.R. and T.B.K. Degree College, Andhra University, Vizag (AP), India
• M.Sc. In Biochemistry CMRIMS College, Bangalore University, Bangalore, Karnataka, India.
• Ph.D In Food Science and Technology
  Department of Agricultural and Food Engineering, Indian Institute of Technology Kharagpur (IIT-KGP), West Bengal, India.
  Thesis title: “Process development and characterization of reconstituted Aloe vera and its high methoxy pectin mixgels"
  Supervisor: Dr.P.Srinivasa Rao Associate professor at IIT-Kharagpur

WORK EXPERIENCE(> 4.5 YEARSPOST PhD)

• Assistant Professor: Department Biosciences, IndrashilUniversity (IU), Rajpur, Ahmedabad,Gujarat, India
• Design course handouts, lab manual, internal committee member for UGC and NAAC visit, organizing members for national conferences and science camp, attended FDP program and workshops, conducted science model presentation etc.
• BSc & MSc Biosciences: Macromolecules structure and functions [BIO-403] [BIO 1-203], Enzymology [BIO-408], Metabolism and Tissue Functions [BIO2 103], Analytical Tools and Techniques [BIO-405], Biochemistry Practical [BIO1106], Ph.D: Computer application in Research [IU SR 02].
• Publication: One research article publishedin Int. J. Biol. Macromol
• Poster presentation: Presented poster in International Symposium on Food Rheology and Structure (ISFRS) at ETH Zurich, Switzerland
• ITS Travel grants: Received 1.32 Lack INR from SERB, India and 500 CHF from ETH, Zurichfor attending ISFRS conference at ETH Zurich, Switzerland.
• Book: Editor of "Recent advances in Food Biotechnology" book for Springer Nature Singapore Pvt. Ltd, Singapore (In Press).
• Book Chapter: One book chapter accepted
• Organizing member (OM): Organized National conference on Synthetic biology and DST Inspire science camps at IU premises.
• Faculty Development Program (FDP):Attended four training programs.
• Workshop (Technical): Attended online workshop on “Introduction to Rheology: on 10-13th Oct 2020, organized by Venture Centre, NCL Pune.
• Training program (TP): Conducted one-week in house training program on HPLC and NMR instrumentation to BSc 6th Sem, 2021 students at IU campus.
• Invited talks: Delivered four talks
• Internal Committee member: NAAC, UGC, science club, Anti-ragging, cultural and Blood Donation camps organizer at Indrashil University
• Projects and patents:Nil
• Assistant Professor:Life Science Finishing School (LSFS), Indrashil Institute ofScienceandTechnology(IIST), Ahmedabad,Gujarat,India.
• Established the R&D lab setups for chemistry and biology branches

RESEARCH EXPERIENCE(2 years)

• SeniorResearchFellowship(SRF) at IIT Kharagpur for a project: “A value chain on Aloe vera Processing (AVC)” funded by the Indian Council of Agricultural Research (ICAR) and National Agricultural Innovation Project (NAIP), NewDelhi, India

ORAL PRESENTATION AWARDS (1)

• Secured 2 nd position in oral presentation during Research Scholars’(RS) day celebration of AGFE department, IIT Kharagpur held on12th December 2015.

INVITED TALKS (4)

• Delivered three talks on food chemistry atTechnology Entrepreneurship Development Program (TEDP) on Food Technology organized by Jyoti Institute of Technology, Bangalore, CIIRC and AIC-JITE, sponsored by NSTEDB-DST, New-Delhi
• Deliver a talk on Novel aspects and challenges of high-demand medicinal plants and its future prospects at Takkur college of Science and Commerce- Mumbai.

MEMBERSHIP (1)

• Indian Society of Rheology(ISR),India

KEY PUBLICATIONS (5)

• P.Kiran, S.Chakraborty, & P.S.Rao, (2018). Rheological, functional and morphological characterization of reconstituted Aloevera gels at different levels of pH and concentration: Novel concepts of reconstituted Aloevera gels formation. Int. J. Biol. Macromol.120(PartA): 414-421. (IF:6.9)
• P.Kiran, N.Swami, and P.S.Rao, (2016) “Viscoelastic behaviour of reconstituted Aloevera hydro gels as a function of concentration and temperature”, Int. Journal of Food Prop: DOI:10.1080/10942912.2016.1168436.(IF:2.7)
• P.Kiran and P.S.Rao, (2016) “Development and characterization of reconstituted hydrogel form Aloe vera (Aloe barbadensis Miller) powder”, J. Food Meas. Charact.10(3): 411-424.(IF:2.4)
• P.Kiran and P.S.Rao, (2014) “Rheological and structural characterization of prepared aqueous Aloevera dispersions”, Food Res Int. 62:1029-1037. (IF:6.4)
• N.Swami,P.Kiran and P.S.Rao, (2014) “Rheological characterization of Aloevera juice concentrates”, J. Food Process Eng.37(4):375-386.(IF:2.3)

BOOKS (1)

• Ajay Kumar, P. Kiran, Vijai Singh, (2021)“RecentAdvancesinFoodBiotechnology" SpringerNature Singapore Pvt.Ltd., Singapore (In press)

BOOK CHAPTER (1)

• K. Gurveer and P. Kiran (2021), “Recent aspects of fortified foods: An overview on field testing tools and fortification program analysis methods”, RecentAdvancesinFood Biotechnology", SpringerNature Singapore Pvt. Ltd., Singapore (Accepted).

NATIONAL/INTERNATIONAL POSTER PRESENTATIONS- (5)

• P. Kiran and P.S.Rao, presentation on “Reconstituted Aloe vera hydrogel formation and its application in high methoxy(HM) pectin mix gel formation” at International symposium on Food Rheology and Structure (ISFRS)-2019 held at ETH University, Zurich, Switzerland (17th-20th June 2019).
• P.Kiran and P.S.Rao, presentation on “Effect of process parameters on the viscoelastic, functional and morphological properties of reconstituted Aloe vera gels”, at International Complex Fluids Conference held at Indian Institute of Science Education and Research (IISER), Pune, India (Jan,2016).
• P.Kiran and P.S.Rao, presentation on “Development of reconstituted Aloe vera (Aloe barbadensis Miller) hydrogels based on rheological characterization”, at National symposium on Complex Fluids held at Engineering Mechanics Unit, JNCASR, Bangalore, India (Dec,2014).
• P.Kiran, S.Mandal, P.S.Rao and A.Chandra, “Effect of biotemplate rheology on properties of multiferroicceramics”, at India-Singapore Joint Physics Symposium held at the Department of Physics, IIT-Kharagpur, India (Feb,2013).
• P.Kiran, S.Mandal, P.S.Rao and A.Chandra, presentation on “Use of biotemplates to tailor the physical properties of multiferroicceramics”, at International Conference on Theoretical and Applied Physics held at the Department of Physics, IIT-Kharagpur, India (Dec,2011).

WORKSHOPS/TRAININGS (6)

• Attended 1 week National level Faculty Development Programme (FDP) on Intellectual property rights for Academia organized by C.K.B Commerce college, Johrat, Assam and CSIR-IICT Hyderabad
• Attended 3 days online workshop on Introduction to Rheology by Dr. Chirag Kalelker (Assistant Professor, Department of Mechanical Engineering, IIT Kharagpur) organized by Venture Centre, NCL Pune.
• Attended 1 day Faculty Development Programme for faculties for technical courses: Indian Institute of Teachers Education (IITE), Gandhinagar, India.
• Attended 5 days AICTE-QIP short term course on “Novel Technologies for Food Product Manufacturing and Shelf-LifeExtension”: Indian Institute of Technology (IIT), Kharagpur
• Attended 1 day “Extended Rheology Characterization” training by Anton Paar at Indian Institute of Technology (IIT), Gandhinagar.
• 4 Months trained in handling analytical instrumentati on HPLC and GC for characterizing pharmaceutical samples viz., tablets, ointments and capsules: Derexlab, Hyderabad, India.

OTHERINFORMATIONS

• Editorial member,Journal name: NA
• Reviewer of Peer-Reviewed journals: Canadian Institute of Food Science and Technology (CIFST), Journal of Food Measurement and Characterization
• Position of responsibility: Two days 24-25th Feb 2011,Organizing secretary in INAE National Symposium on Emerging Innovative Technologiesfor Assurance of Quality and Safety in Processed Food (FoQSAT2011): Agricultural and Food Engineering Department, IIT-Kharagpur.

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EDUCATIONAL QUALIFICATION

• UG : B Sc Biotechnology (2012), Saurashtra University, Rajkot.
• PG : M Sc Biotechnology (2014), Nirma University, Ahmedabad.
• Ph.D : Microbiology (2018), M K Bhavnagar University, Bhavnagar.

EXEPERIENCE / RESEARCH / PUBLICATIONS

• Total Experience in Years : 7 years
• Area of Expertise : Environmental microbiology and biotechnology, Industrial microbiology and biotechnology, molecular biology, metagenomics
• Total publications : 25 (17 research articles, 2 books and 6 book chapters (Cumulative impact factor: 54.95))
• Total Papers Presented : 6 papers
• Honor/ Award : CSIR Travel award – Full airfare support

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EDUCATIONAL QUALIFICATION

• Ph.D : D. (Animal Biotechnology), 2017, ICAR-National Dairy Research Institute, Karnal, Haryana, India.
• PG : (Biotechnology), 2011, Department of Biotechnology, Kurukshetra University, Kurukshetra, Haryana, India.
• UG : B.Sc. (Zoology, Botany, Chemistry), 2004, GNG College, Kurukshetra University, Kurukshetra, Haryana, India

WORK EXPERIENCE

• Assistant Professor (06/2018-ongoing), Indrashil University, Rajpur, Mehsana, Gujarat, India
• Assistant Professor (12/2017-04/2018), Sharda University, Greater Noida, U.P. India

SUBJECTS TAUGHT

• Cell Biology [BIO-401] [BIO 2 104]
• Enzymology [BIO-405]BIO 2 201
• Genetic Engineering [BIO 403]
• Recombinant DNA Technology [BIO 3 205]
• Analytical Tools and Techniques [BIO-406]
• Cell Biology and Enzymology Lab [BIO 1 105]

RESEARCH AREA

Area of Interest : Host-pathogen and Host-probiotics interaction studies, Molecular gene cloning, expression and purification of proteins (probiotics, plants and mammals), biophysical and structural analysis of proteins, animal cell and tissue culture (Immunostaining, pathogen exclusion assays Previously, I have done cloning, expression and purification of surface layer proteins (Slps) of three different species of probiotic lactic acid bacteria along with functional and physicochemical analysis of these rec. proteins. The study revealed the possible role of Slps in mediating binding of probiotics with host tissues and that they could be used to compete and exclude the binding of pathogens, so these proteins may find application in the prophylaxis of mucosal infections.

Role of these proteins in adhesion and pathogen exclusion from human intestinal cells and tissue were determined using Caco-2, HT-29 cell lines (human intestinal cell lines) and human intestinal tissue. Binding potentials of these proteins to intestinal cell lines were observed by immunofluorescence and pathogen exclusion ability was analyzed by pour plating method. Biophysical analysis of Surface layer proteins was done i.e. Thermal denaturation by UV-Visible spectrophotometer, Secondary structure determination by Circular Dichroism, pH stability by fluorescence spectrophotometer. Immunomodulatory roles of Slps were determined by analyzing up and down regulation of inflammatory cytokines (Real-time PCR).

PROJECTS

• Preparation of florescent bricks’ sponsored by Atal Incubation Centre (worth- 2 lakhs)
  • Group – Ms. Shipra Pandey and other M. Sc student

HONOR/AWARD

• Probiotic Association of India (Pai)

KEY PUBLICATIONS

• P R Chandhni, Diwas Pradhan, Kandukuri Sowmya, Sunny Gupta, Saurabh Kadyan, Ritu Choudhary, Gulati Ganga, Rashmi Hogarehalli Mallappa, Jai K Kaushik and Sunita Grover. 2021. Ameliorative Effect of Surface Proteins of Probiotic Lactobacilli in Colitis Mouse Models. Frontiers in Microbiology. 175.
• Kumar Siddarth Singh, Ritu Choudhary, Sonu Bisht, Sudarshan Kumar, Ashok Kumar Mohanty and Jai Kumar Kaushik. 2017. Expression of recombinant truncated domains of mucus-binding (Mub) protein of Lactobacillus plantarum in soluble and biologically active form. Protein expression and purification. 135:54-60
• Sonu Bisht , Kumar Siddarth Singh, Ritu Choudhary, Sudarshan Kumar, Ashok Kumar Mohanty and Jai Kumar Kaushik. 2017. Expression of fibronectin-binding protein of L. acidophilus NCFM and in vitro refolding to adhesion capable native-like protein from inclusion bodies. Protein expression and purification. 135:54-60

BOOK CHAPTERS

• DNA structure and function. A series of life sciences books. Springer nature (under publication)

CONFERENCES

• Ritu Choudhary and J. K. Kaushik. 2021. Recombinant surface layer protein of Lactobacillus helveticus inhibits the binding of enterotoxigenic E. coli to human intestinal cell line. "E-symposium on recent trend in biology organized by Charusat University, Changa , Gujarat”
• Ritu Choudhary and J. K. Kaushik. 2021. Surface layer protein of probiotic Lactobacillus acidophilus NCFM prevents the Enterotoxigenic E. Coli adhesion to Caco-2 cells. "Virtual 22nd INDO-US Flow Cytometry Workshop”
• Ritu Choudhary and J. K. Kaushik. 2019. Probiotic recombinant adhesive surface layer protein prevents the binding of enteric pathogen to human intestinal cell line HT-29. "International Conference on Advances in Medical and Industrial Biotechnology”.
• Ritu Choudhary, Kumar Siddarth Singh, Sonu Bisht and Jai K. Kaushik. 2017. Recombinant surface layer proteins of Lactobacillus acidophilus NCFM inhibits the adhesion of enterotoxigenic E. coli to the human intestinal cell line Caco-2. “International Conference on crystal ball vision on science and technology for societal upliftment”.
• Ritu Choudhary and Jai K Kaushik.2016. Purification and characterization of recombinant surface layer protein of probiotic lactic acid bacteria. Review – CAFT training programme on “Probiotics: The Therapeutics of 21st Century organized by ICAR.
• Ritu Choudhary, Kumar Siddarth Singh, SonuBisht and Jai K. Kaushik.2016. Host-microbial interaction:Role of surface proteins of probiotic lactic acid bacteria in binding with host. Review – CAFT training programme on “Probiotics: The Therapeutics of 21st Century organized byICAR.
• Choudhary, R., Singh, K. S., Bisht,S., Kaur, S., Grover, S., Kumar, S., Mohanty, A. K., Kaushik, J. K. 2016.S-layer proteins of lactobacilli inhibits ETEC adhesion to the human intestinal cells and modulates innate immune response of mice immune cells. 3rd Biennial PAi Conference -51 (Young Investigator award – PAi conference and international symposium on Stress, Microbiome and Probiotics.
• Choudhary, R., Singh, K.S., Kumar, S., Grover, S., Kaushik J.K. 2014. Pathogen Exclusion by Surface Proteins: Interaction of recombinant surface layer protein of lactobacilli with human gt cell line and tissues. 2nd Annual Conference of Probiotic Association of India (PAi) and the International Symposium on “Probiotics and Microbiome: Gut and Beyond”
• Singh, K.S., Choudhary, R., Kumar, S., Grover, S., Kaushik J.K. 2014. Muco-adhesive potential in domains of mucus binding protein (Mub) of Lactobacillus plantarum. 2nd Annual Conference of Probiotic Association of India (PAi) and the International Symposium on “Probiotics and Microbiome: Gut and Beyond”Muco-adhesive potential in domains of mucus binding protein (Mub) of Lactobacillus plantarum

TRAINING AND CONFERENCES ATTENDED

• Project report on “DNA Fingerprinting” from June 8thto August 13th, 2010at DNA Division, Forensic Science Lab, Madhuban, Karnal, Haryana
• National Symposium on “Recent advances in Reproductive Biotechnology: Retrospective and Prospective Vision” January 30-31, 2012 organized by Indian Society for the study of Reproduction & Fertility (ISSRF)
• International Workshop on “Transcriptomics, Proteomics and Structural Biology” organized by ABTC, NDRI and NBAGR, Karnal on February 27-29, 2012
• Training on “Computational Tools for Animal Genome Resource Data Analysis” during December 02-13, 2013 organized under NAIP subproject “Establishment of National Agricultural Bioinformatics Grid (NABG) in ICAR”
• 2nd Annual Conference of Probiotic Association of India (PAi) and the International Symposium on “Probiotics and Microbiome: Gut and Beyond” at New Delhi on November 3-4, 2014
• “National Workshop on Proteomics Structural Bioinformatics” organized by The BTIS Sub-centre supported by Department of Biotechnology (DBT), Govt. of India on March 23-25, 2015
• 3rd Biennial PAi conference and International Symposium on “Stress, Microbiome and Probiotics” organized by PAi and NISER, Bhubaneswar on March 11-13, 2016.

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EDUCATIONAL QUALIFICATION

• UG : Microbiology, Sardar patel university Vallabh vidyanagar (2006).
• PG : Zoology, Sardar patel university Vallabh vidyanagar (2009).
• M.Phil : Gujarat university, Ahmedabad, 2015.
• Ph.D : Zoology, Sardar patel university Vallabh vidyanagar (2015).

EXEPERIENCE / RESEARCH / PUBLICATIONS

• Total Experience in Years : 5 years
• Area of Research : : physiology, metabolic disorders, fluoride toxicity, ethnopharmacology, nutraceuticals, formulated food
• Total Papers Published : 6 papers
• Total Papers Presented : 10 papers

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EDUCATIONAL QUALIFICATION

• UG : B.Sc. (Microbiology), Maharaja Krishnakumarsinhji Bhavnagar University, 2008.
• PG : M.Sc. (Microbiology),Maharaja Krishnakumarsinhji Bhavnagar University, 2010.
• Ph.D : (Microbiology), Maharaja Krishnakumarsinhji Bhavnagar University, 2017.

EXEPERIENCE / RESEARCH / PUBLICATIONS

• Total Experience in Years : 7 years
• Area of Research : Microbiology, Environmental Biology
• Total Papers Published : 4 papers
• Total Papers Presented : 3 papers

EDUCATIONAL QUALIFICATION

• UG : Bachelor Degree, University of Mumbai, Mumbai, 2011.
• PG : Master Degree, University of Mumbai, Mumbai, 2013.
• M.Phil : Gujarat university, Ahmedabad, 2015.
• Ph.D : Gujarat University, Ahmedabad, 2019.

EXEPERIENCE / RESEARCH / PUBLICATIONS

• Total Experience in Years : 4 years
• Area of Research : Taxonomy, Ecology
• Total Papers Published : 8 papers
• Total Papers Presented : 3 papers

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• Publications : 92 [84 Journals, 5 Book Chapters 3 Books,]
• Conferences : 18 [11 International, 7 National]
• Personal : Born Sep 21, 1977; Male; Married; Indian
• Google citations : 2000
• H-Index : 23
• Post Ph.D. experience : 12+ Years

Professional & Research Experiences

• Associate Professor : Department of Chemistry, Indrashil University,Rajpur, Mehsana, India (08/2018- Present)
• CSIR-SRA (Scientist’s Pool) : Polymers & Functional Materials Division, CSIRIndian Institute of Chemical Technology, Hyderabad, India (07/2015-06/2018)
• RMIT-Research Associate : RMIT-IICT Research Centre, CSIR-Indian Institute of Chemical Technology, Hyderabad, India (04/2013-06/2015)
• Postdoctoral Researcher : Freiburg Institute for Advance Studies (FRIAS), Freiburg, Germany (04/2011-10/2012)
• SNSF-Postdoctoral Fellow : Massachusetts Institute of Technology (MIT), Cambridge, USA (03/2010-02/2011)
• Research Assistant : Department of Chemistry, Swami Ramanand Teerth Marathwada University, Nanded, India (03/2003-06/2005)

Academic Qualifications

• Ph.D. : (Chemistry, DOI: 10.13097/archive-ouverte/unige:6528) Supervised by Prof. Stefan Matile at University of Geneva, Geneva (Switzerland) -26/11/2009
• M.Sc. : (Organic Chemistry, 67.84%) at Swami Ramanand Teerth Marathwada University, Nanded (India)-2002

Academic Awards

• 2015 : CSIR-Senior Research Associateship (Scientists’ Pool Scheme) Award.
• 2010 : Swiss National Science Foundation (SNSF) Postdoctoral Fellowship Award.
• 2006 : Ph.D. Fellowship Award, University of Geneva, Switzerland.

Academic Administrative Experience

• HoD : Chemistry, Indrashil University (June 2020- present).
  - Member, Institutional Biosafety Committee, Indrashil University (March 2020-present)
  - Member, Recruitment Committee, School of Sciences, Indrashil University (2019 - 2021)
  - Member, Academic council, Indrashil University (August 2020- present)
  - Member, Board of Study, Indrashil University (June 2019 – present)
  - Member, Doctoral Research Committee (DRC), Indrashil University (July 2019-present)
• Nodal Office : Indrashil University, for SHODH (ScHeme of Developing High Quality Research)scheme, Knowledge Consortium of Gujarat, Department of Education, Government of Gujarat (2019–present)
• Ph.D. Coordinator : Performing duty as coordinator of Ph.D. Section, Indrashil University (July 2021 – present)
• External Affair Coordinator : Performing duty as SOS external affair coordinator, Indrashil University (January 2022 – present)
• National Education Policy (NEP) 2020 Coordinator : Performing duty as NEP-2020 coordinator of Indrashil University (June 2021 - present)
• Seminar Coordinator : School of Sciences, Indrashil University (academic year 2018-2019)
• Organizing Secretary : Organized a first national conference on synthetic biology for reprogramming cells, Indrashil University (24th - 25th January 2020)
• Workshop Convenor : Organized a “Indo-Australia Workshop on Advanced Functional Materials-2021 (IAWAM-2021)”, Indrashil University (11th – 13th November 2021)
• Jury : Attended and evaluated posters in “Science and Start-up Conclave, “eUReka 3.0-2020” on 30th January, 2020, at Institute of Advanced Research, Gandhinagar

Scientific Administrative Experience

• Associate Editor : ‘Frontiers in Chemistry’ (IF: 5.2) in the supramolecular chemistry section
• Guest Associate Editor : Topic: New Approaches in Toxicity Testing of Nano therapeutics; ‘Frontiers in Pharmacology’ (IF: 5.8)
• Journal Reviewer : Materials (MDPI), Chemical Communication, RSC Advances, Chemistry Select, Tetrahedron Letter, Synthetic Communication, Synthetic Letter
• Thesis Reviewer : Invited as external reviewer for Master and PhD thesis from: Central University of Gujarat, ICT-Mumbai, CSIR-IICT Hyderabad, SRTM University Nanded, Shivaji University Kolhapur

Research Project

• CSIR-SRA (Pool Officer;(18,00,000 Rs) 2015-2018 : Design, synthesis and photovoltaic characterization of phosphole bearing conjugated copolymers: A new family of electron-acceptors
• Swiss SNSF Project (44,500 US$) 2010-2011 : Nanostructured Organic Electronic Materials for Chemical and Biological Sensing

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EDUCATIONAL QUALIFICATION

• UG : National College, Bangalore University, Karnataka 1997.
• PG : Chemistry, Bangalore University, 2000.
• Ph.D : Chemistry, National Chemical Laboratory, Pune, 2007.
• Other Qualification : Postdoctoral Fellow, Brandeis University, USA, 2007
  Postdoctoral Fellow, University of California, Los Angeles, USA 2009
  Postdoctoral Research Associate, University of Leeds, UK, 2011.
  Marie-Curie Research Fellow, Durham University, UK 2013.
  Assistant Professor (Adhoc), NIT, Calicut, India 2016.

RESEARCH / PUBLICATIONS / MEMBERSHIPS / AWARDS

• Total Experience in Years : 12 years
• Area of Research : Material Chemistry
• Total Papers Published : 21 papers
• Total Papers Presented : 3 papers
• Total Books Published : 1 book
• Award: Marie-Curie International Fellowship 2013.
• Other Achievements : Member of the organizing committee ‘Small molecule and macromolecular Bruker X-ray workshop and conference, 28-29 Jan 2008, MIT, USA’. Conducted workshop on UHV.

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EDUCATIONAL QUALIFICATION

• UG : Chemistry Honors Presidency College, Calcutta University, 2000.
• PG : Chemistry, IIT Kanpur,2002., Chemistry, Washington University in St. Louis USA, 2005.
• Ph.D : Chemical Sciences, CSIR National Chemical Laboratory, 2019.

EXEPERIENCE / RESEARCH / PUBLICATIONS

• Total Experience in Years : 8 years
• Area of Research : Surface modification of polymers, metallic and polymeric nanoparticle synthesis, drug delivery, tissue engineering
• Total Papers Published : 15 papers
• Total Papers Presented : 12 papers
• Total Book Chapters Published : 2 books
• Awards : DST Women Scientist Fellowship January 2014 till July 2017,
  CSIR SRF Fellowship June 2013 (discontinued),
  Graduate Students Fellowship and teaching assistantship from Washington University in St. Louis A & S,
  Graduate Aptitude Test for Engineering (2002): 98.35 percentile (All India Rank 41),
  National Eligibility Test (NET) 2002: UGC-JRF (Junior Research Fellowship),
  Indian Academy of Sciences Fellowship: Summer 2001.

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EDUCATIONAL QUALIFICATION

• Doctor of Philosophy (Ph.D.), Supersonic Jet Spectroscopy, 2017, IIT Bombay.
• Masters of Science (M.Sc.), Physics, 2007, DDU Gorakhpur University.
• Bachelor of Science (B.Sc.), Physics, Chemistry, Maths, 2005, DDU Gorakhpur University.

Work Experience

• Jan’ 2010 – Dec’ 2011 Junior Research Fellow IIT Bombay, Mumbai, Maharashtra
• Jan’ 2012 – May’2017 Senior Research Fellow IIT Bombay, Mumbai, Maharashtra
• June’ 2017 – Aug’ 2017 Research Associate IIT Bombay, Mumbai, Maharashtra
• Aug’ 2017 – Dec’2017 Assistant Professor MM (Deemed to be) University, Ambala, Haryana
• Jan’2018 – May’2018 Visiting Faculty ShriVaishnavVidyapeethVishwavidyalaya, Indore, Madhya Pradesh
• July’2018 – May’2019 Teaching Assistant SV NIT Surat, Gujarat
• Aug’2019 – Dec’2019 Assistant Professor (Adhoc) NIT Warangal, Telangana
• Feb’2020 – Aug’2020 Assistant Professor Adama Science & Technology University (ASTU), Ethiopia
• Sept’2020 – Present Assistant Professor Indrashil University, Ahmedabad

Details of paper published in Journals

• International Journals –8(Including 7 Research Articles, and 1Book Chapters)
• Google Scholar: https://scholar.google.com/citations?user=0-0NrXMAAAAJ&hl=en&authuser=1
• Academia.edu Profile: https://iitb.academia.edu/ankitsrivastava
• Research Gate Profile:https://www.researchgate.net/profile/Ankit_Kumar_Srivastava

Details of paper published in Conferences

• National Conferences :2
• International Conferences :4

No. of Awards Received and its Details–3

• CSIR-UGC (NET) in Physical Sciences – 2009
• GATE in Physics – 2009
• NGPE (National Graduate Physics Examination) conducted by IAPT – 2004

EDUCATIONAL QUALIFICATION

• UG : B. Sc. (Pharmaceutical Chemistry), Holkar Science College, Devi Ahilya VishwaVidyalaya Indore (2001).
• PG : M. Sc. (Life Sciences) Devi Ahilya VishwaVidyalaya, Indore (2004).
• Ph. D. : Indian Institute of Technology- Kanpur (2010).

Work Experience

• Aug 2021- Present, Associate Professor, Indrashil University
• Jul 2019- Present, Assistant Professor, Indrashil University
• Aug, 2016- Jul, 2019, Assistant Professor, Indian Institute of Advanced Research, Gandhinagar, Gujarat, India
• May, 2015 – Apr, 2017, Visiting Faculty, Indian Institute of Advanced Research, Gandhinagar and Central University of Gujarat
• July, 2013-July, 2014, CSGI Postdoctoral Fellow, University of Florence, Italy
• Jul, 2011 – Jun 2013, Post Doctoral Research Fellow, University of Geneva, Switzerland
• Nov, 2010- Jun 2011, Research Fellow, Albert Einstein College of Medicine, New York, USA
• Apr 2010-Oct-2010, Visiting Fellow, Tata Institute of Fundamental Research, Mumbai, India

Details of paper published in Journals (numbers):

• International Journals – 21 (Including 17 research articles, 4 book chapters;
  Total citations: 330, h-index 12)
• Google scholar link: https://scholar.google.com/citations?user=XuoJoLcAAAAJ&hl=en

Details of paper published in Conferences (numbers):

• National Conferences : 6
• International Conferences : 17

No. of Awards/ Grants Received and its Details–8

• Awarded SERB POWER Grant in 2021 and received Grant Amount of 28,90,000 INR for 3 years. The Grant is given to promising woman Scientists of India to encourage their research
• Awarded Newton Researcher links Workshop Grant 2017 as an initiative from Newton Fund Scheme for encouraging collaboration between Early career researchers from India and UK
• Received extramural research grant in 2016 from DST SERB as a Principal Investigator Project title: ‘A novel nanoparticle-based bioassay for sensitive detection of cancer-specific proteases.’ Grant amount ~ 67 lacs.
• PhD thesis was selected for 2nd Prize of “2010 Eli Lilly and Company Asia Outstanding Thesis Awards”.
• Received CSGI Postdoctoral Research Grant for conducting research in lipid oligonucleotide conjugates in University of Florence, Italy
• Received Visiting Fellowships from Albert Einstein College of Medicine, New York, USA and Tata Institute of Fundamental Research, Mumbai India.
• Received Postdoctoral Research Fellowship from Swiss National Science Foundation for conducting research on polymer and peptide self-assemblies.
• Secured 99.55% and All India Rank 22nd in Graduate Aptitude Test in Engineering (GATE).

M.Sc/M.Tech Thesis Guided

• Pruthvi Upadhyay (M.Tech, Mumbai University)
• Jainisha Patel (M.Sc. Project student, IAR)
• Yash Barot (M.Sc. Project student, IAR)
• Harshil Patel (M.Sc. Project student, IAR)
• Krupali Hun (M.Sc. Project student, VNSU, Surat)
• Rasila Chaudhary (M.Sc. Project student, Indrashil University)
• Mayuri Sojitra (M.Sc. Project student, VNSU, Surat)
• Yogesh Bhoya (M.sc Project student, Indrashil University)
• Rasila Parmar (M.sc Project student, Indrashil University)
• Rutik Majethiya (B.Tech Project student, IAR) Bhamini Vasava (M.sc Project student, Indrashil University)
• Alita Gamit (M.sc Project student, Indrashil University)
• Ankesh Patel M.sc Project student, Indrashil University)
• Ankita Gamit (M.sc Project student, Indrashil University)

International/National Collaborations

• Prof. Ehud Gazit (Tel. Aviv University, Israel)
• Dr. Manoj Pandey (PDPU, Gujarat)
• Dr. K. B. Joshi (Sagar University, M. P.)
• Dr. Dhiraj Bhatia (IIT Gandhinagar)
• Dr. Dhiraj K. Singh (IITRAM)
• Dr. Danil Bukhvalov (Nanjing Forestry University, China)

Research Interest and Future Plan

• Single amino acid self-assembly and its association with IEMs and amyloid diseases: There are many diseases which are caused by the accumulation of amino acids due to inborn errors of metabolism (IEM). Our aim is to understand the molecular mechanism of these IEM by assessing self-association of amino acids
• Controlled self-assembly of modified single amino acids: There is an ever increasing demand to find new scaffold for the design of novel micro/nanoarchitectures which can be of potential interest for diverse applications in material science. In this direction, we are interested in assessing the self-assembly of modified single amino acids under controlled condition. The project aims to find a very simple and facile route for synthesis of novel scaffold for self-assembly.
• Assessing aggregation properties of heterocyclic compounds for their application as dye and in sensing: The main objective of this project is to synthesize heterocyclic compounds which can potentially be used as dyes and sensors. Our studies also suggest there is direct correlation between aggregation properties and photophysical characteristic of compounds. Some dyes reveal enhanced fluorescence on aggregation as in aggregation induced emission dyes which some other reveal better fluorescence on disaggregation
• Nanoparticle based assay: The main goal of these projects will be to design safe and efficient nanoparticle-based products for imaging and diagnosis of diseases like cancer. We have already efficiently designed gold nanoparticlebased assay for facile detection of amyloid inhibitors. We want to develop more novel assay for detection of analyte in minute amounts in future.

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